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Dr. Cantley and his team in their lab at Weill Cornell Medical College.

Lab Team

The Cantley lab welcomes a diverse set of talents and fosters an interdisciplinary approach in its attempts to translate fundamental scientific discoveries into clinical innovations.

Principal Investigator

Lewis Cantley

Lewis C. Cantley, Ph.D.

Professor of Cancer Biology in Medicine
Lewis Cantley has made significant advances in cancer research, stemming from his discovery of the signaling pathway phosphoinositide 3-kinase (PI3K) in 1984. His pioneering research has resulted in revolutionary treatments for cancer, diabetes and autoimmune diseases. The author of over 400 original papers and more than 50 book chapters and review articles, Dr. Cantley is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. He graduated summa cum laude with a B.S. in chemistry from West Virginia Wesleyan College (1971) and obtained a Ph.D. in biophysical chemistry from Cornell University (1975). He conducted postdoctoral research at Harvard University, where he was appointed assistant professor of biochemistry and molecular biology in 1978. He became a professor of physiology at Tufts University in 1985, but returned to Harvard Medical School as professor of cell biology in 1992. He became chief of Harvard’s new Division of Signal Transduction, and a founding member of its Department of Systems Biology in 2002. In 2007, he was appointed director of the Beth Israel Deaconess Cancer Center. He joined the faculty of Weill Cornell Medical College and NewYork-Presbyterian Hospital in 2012.

Lab Members

Guillermo Burgos Barragan PhD

Guillermo Burgos Barragan PhD

  • Postdoctoral Associate
Research Focus: Metabolism and genomic instability in cancer.

Maira  DiTano

Maira diTano PhD

  • Postdoctoral Associate
Research Focus: I have joined the Cantley laboratory at Weill Cornell Medicine to pursue my interest in cancer metabolism. Here, I study pancreatic cancer, which is one of the deadliest tumor types. I am investigating how genetic and metabolic features of BRCA2-deficient pancreatic tumors may lead to vulnerabilities that can be therapeutically targeted and translated from bench to bedside.

Johnson

Jared Johnson Ph.D.

  • Postdoctoral Associate
Research Focus: Molecular and biochemical approaches to the signaling and metabolism of cancers

  • Ph.D.
    Cornell University

Edward Kastenhuber PhD

  • Postdoctoral Associate
  • B.S.E.
    University of Pittsburgh
  • Ph.D.
    Gerstner Sloan Kettering Graduate School of Biomedical Sciences
Valbona Luga

Valbona Luga Ph.D.

  • Postdoctoral Associate
Research Focus: LKB1/AMPK Signaling and Peutz-Jeghers Syndrome

  • Ph.D.
    University of Toronto (Canada)
  • B.Sc.
    University of Toronto (Canada)
Evan Noch

Evan Noch M.D., Ph.D.

  • Instructor, Department of Neurology
  • Post-doctoral fellow
Research Focus: Evan Noch is Assistant Professor of Neurology within the Division of Neuro-oncology at Weill Cornell Medicine. His overall research focus is to leverage drug and dietary therapies for the treatment of glioblastoma. He discovered a novel mechanism of cysteine susceptibility and redox regulation in glioblastoma and uses FDA-approved drugs to target this pathway in mouse models of glioblastoma. He also works to enhance targeted therapies for glioblastoma by identifying and blocking mechanisms of resistance.

  • Ph.D.
    Temple University School of Medicine
  • M.D.
    Temple University School of Medicine
  • B.S.
    New York University
Laura Palma

Laura Palma

Research Focus: Molecular mechanisms and glucose metabolism in glioblastoma

Headshot of Ruth Silimon

Ruth Silimon

  • Graduate Student
Research Focus: Skeletal muscle growth, metabolism, and muscle loss in cancer.

Headshot of Janet Sun

Janet Sun

  • Lab Manager
  • B.S.
    St. Lawrence University
Samuel Taylor

Samuel Taylor

  • MD, PhD student
Research Focus: (1) Elucidating the mechanisms of intestinal tumor growth (2) Dissecting the role of pyruvate kinase in modulating cellular nutrient utilization (3) Characterizing metabolic adaptations to hostile cell environments

  • BS
    Yale University
Headshot of David Wu

David Wu

  • Research Technician II
Research Focus: Maintaining mouse colonies and mouse experiments

  • B.S.
    Stony Brook
Tomer Yaron

Tomer Yaron

  • Graduate Student (Tri-I CBM)
Research Focus: (1) Computational development of the Kinase Library – a novel system for predicting upstream kinases for phosphorylation events. (2) Phospho-antigens – investigating the presentation mechanism and specificity of phosphorylated antigens on MHC Class I. (3) MHC Library – characterizing the binding specificity of different MHC Class I molecules.

  • M.Sc.
    Bar-Ilan University, Israel.
  • B.Sc.
    Bar-Ilan University, Israel.

Weill Cornell Medicine
Cantley Lab
Weill Cornell Medical College Meyer Cancer Center
Belfer Research Building
413 E 69th St.
Room 1362, Box 50
New York, NY 10021 Phone: (646) 962-6297