Cantley Lab

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Dr. Cantley and his team in their lab at Weill Cornell Medical College.

Lab Team

The Cantley lab welcomes a diverse set of talents and fosters an interdisciplinary approach in its attempts to translate fundamental scientific discoveries into clinical innovations.

Principal Investigator

Lewis Cantley

Lewis C. Cantley, Ph.D.

Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medical College, Professor of Cancer Biology in Medicine
Lewis Cantley has made significant advances in cancer research, stemming from his discovery of the signaling pathway phosphoinositide 3-kinase (PI3K) in 1984. His pioneering research has resulted in revolutionary treatments for cancer, diabetes and autoimmune diseases. The author of over 400 original papers and more than 50 book chapters and review articles, Dr. Cantley is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. He graduated summa cum laude with a B.S. in chemistry from West Virginia Wesleyan College (1971) and obtained a Ph.D. in biophysical chemistry from Cornell University (1975). He conducted postdoctoral research at Harvard University, where he was appointed assistant professor of biochemistry and molecular biology in 1978. He became a professor of physiology at Tufts University in 1985, but returned to Harvard Medical School as professor of cell biology in 1992. He became chief of Harvard’s new Division of Signal Transduction, and a founding member of its Department of Systems Biology in 2002. In 2007, he was appointed director of the Beth Israel Deaconess Cancer Center. He joined the faculty of Weill Cornell Medical College and NewYork-Presbyterian Hospital in 2012.

Lab Members

Headshot of Jacqueline  Gonzalez

Jacqueline Gonzalez B.Sc.

  • Administrative Assistant to Dr. Lewis Cantley
Phone: (646) 962-6132
Monica Rosen. Cantley lab manager

Monica Rosen

  • Lab Manager
  • B.S.
    Pennsylvania State University
Phone: (646) 962-6136
Johnson

Jared Johnson Ph.D.

  • Postdoctoral Associate
Research Focus: Molecular and biochemical approaches to the signaling and metabolism of cancers

  • Ph.D.
    Cornell University
Headshot of Ting-Yu (Molly) Lin

Ting-Yu (Molly) Lin

  • Graduate Student
Research Focus: Regulation of NRF2 in the Non-Small Cell Lung Cancer (NSCLC).

  • M.S.
    National Taiwan University (Taipei, Taiwan)
Valbona Luga

Valbona Luga Ph.D.

  • Postdoctoral Associate
Research Focus: LKB1/AMPK Signaling and Peutz-Jeghers Syndrome

  • Ph.D.
    University of Toronto (Canada)
  • B.Sc.
    University of Toronto (Canada)
Headshot of Bryan Ngo

Bryan Ngo

  • Graduate Student
Research Focus: (1) Defining the molecular basis of LKB1-HIPPO pathway mediated tumor suppression in KRAS-Driven Non-Small Cell Lung Cancer. (2) Identifying molecular convergence points between the Hippo Pathway and Phosphoinositide (PI) Kinases, with an emphasis on the Type II PI Kinase, PIP4K2s.

  • B.S.
    University of California, Irvine
Noch

Evan Noch M.D., Ph.D.

  • Instructor, Department of Neurology
  • Post-doctoral fellow
Research Focus: The molecular mechanisms of endogenous tumor-associated necrosis in glioblastoma as well as the regulation of glucose metabolism using targeted therapies and dietary strategies to treat glioblastoma. Within this research program, he uses patient-derived models of glioblastoma to better recapitulate the human disease state and employs a wide variety of available technologies and core facilities within the tri-institutional community. He hopes to improve not only patient outcomes and survival but also overall well-being during treatment, particularly with respect to tumor necrosis that can be a devastating aspect of this tumor type and a major adverse effect of current treatment.

  • Ph.D.
    Temple University School of Medicine
  • M.D.
    Temple University School of Medicine
  • B.S.
    New York University
Headshot of Ruth Silimon

Ruth Silimon

  • Graduate Student
Research Focus: Skeletal muscle growth, metabolism, and muscle loss in cancer.

Headshot of Janet Sun

Janet Sun

  • Research Technician II
Research Focus: Type-2 PIP kinases and kinase signaling

  • B.S.
    St. Lawrence University
Photo of Jenny Wong

Jenny (Chan Ying) Wong

  • Research Technician II
Research Focus: Kinase signaling

  • M.S.
    City College of New York
  • B.S.
    City College of New York
Headshot of David Wu

David Wu

  • Research Technician II
Research Focus: Maintaining mouse colonies and mouse experiments

  • B.S.
    Stony Brook

Weill Cornell Medicine
Cantley Lab
Weill Cornell Medical College Meyer Cancer Center
Belfer Research Building
413 E 69th St.
Room 1362, Box 50
New York, NY 10021 Phone: (646) 962-6297