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Lab Team

Dr. Cantley's Lab Team

Dr. Cantley and his team in their lab at Weill Cornell Medical College.

The Cantley lab welcomes a diverse set of talents and fosters an interdisciplinary approach in its attempts to translate fundamental scientific discoveries into clinical innovations.

Principal Investigator

Lewis Cantley

Lewis C. Cantley, Ph.D.

Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medical College/Ronald P. Stanton Clinical Cancer Program at NewYork-Presbyterian , Professor of Cancer Biology in Medicine
Lewis Cantley has made significant advances in cancer research, stemming from his discovery of the signaling pathway phosphoinositide 3-kinase (PI3K) in 1984. His pioneering research has resulted in revolutionary treatments for cancer, diabetes and autoimmune diseases. The author of over 400 original papers and more than 50 book chapters and review articles, Dr. Cantley is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. He graduated summa cum laude with a B.S. in chemistry from West Virginia Wesleyan College (1971) and obtained a Ph.D. in biophysical chemistry from Cornell University (1975). He conducted postdoctoral research at Harvard University, where he was appointed assistant professor of biochemistry and molecular biology in 1978. He became a professor of physiology at Tufts University in 1985, but returned to Harvard Medical School as professor of cell biology in 1992. He became chief of Harvard’s new Division of Signal Transduction, and a founding member of its Department of Systems Biology in 2002. In 2007, he was appointed director of the Beth Israel Deaconess Cancer Center. He joined the faculty of Weill Cornell Medical College and NewYork-Presbyterian Hospital in 2012.

Lab Members

Jacqueline Gonzalez, Cantley assistant

Jacqueline Gonzalez B.Sc.

Administrative Assistant to Dr. Lewis Cantley

Phone: 646-962-6132
Monica Rosen. Cantley lab manager

Monica Rosen B.S.

Lab Manager

Phone: (646) 962-6136

Kaitlyn Bosch B.S.

Research Technician

Research Focus: GEMMs in colorectal cancer and cancer metabolism

DeNicola

Gina M. DeNicola Ph.D.

Postdoctoral Associate

Research Focus: NRF2 Activity in Pancreatic Cancer

Ph.D.
University of Pennsylvania

B.S.
Pennsylvania State University

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Emerling

Brooke M. Emerling Ph.D.

Instructor of Cancer Biology

Research Focus: The Role of the Phosphatidylinositol 5-Phosphate 4-Kinases in p53 Null Breast Cancers

Ph.D.
Northwestern University

B.A.
University of California-Santa Cruz

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Marcus Goncalves M.D., Ph.D.

Endocrinology Fellow

Research Focus: Skeletal muscle growth and metabolism, Muscle loss in cancer, Glucose metabolism, Insulin signaling, PI5P4K

M.D., Ph.D.
University of Pennsylvania School of Medicine

BS, MSE
Johns Hopkins University

Hodakoski

Cindy Hodakoski Ph.D.

Postdoctoral Associate

Research Focus: Studying glucose dependence and AMPK signaling regulation in lung cancer cells.

Ph.D.
Columbia University

B.A.
University of Scranton

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Hopkins

Ben Hopkins Ph.D.

Postdoctoral Associate

Research Focus: The role of insulin signaling in pancreatic cancer; how insulin signaling impacts KRAS driven disease progression and how these signaling networks can be targeted for therapeutic benefit.

Ph.D.
Columbia University

M.A.
Yale University

B.A.
Amherst College

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Johnson

Jared Johnson Ph.D.

Postdoctoral Associate

Research Focus: Molecular and biochemical approaches to the signaling and metabolism of cancers

Ph.D.
Cornell University

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Karreth

Florian Karreth Ph.D.

Postdoctoral Associate

Research Focus: The role of competitive endogenous RNAs in cancer as well as on the identification of mediators of prostate cancer bone metastasis.

Ph.D.
University of Vienna (Austria)

M.Sc.
University of Vienna (Austria)

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Ting-Yu (Molly) Lin

Graduate Student

Research Focus: Regulation of NRF2 in the Non-Small Cell Lung Cancer (NSCLC).

M.S.
National Taiwan University (Taipei, Taiwan)

Ryan Loughran B.S.

Research Technician

Valbona Luga

Valbona Luga Ph.D.

Postdoctoral Associate

Research Focus: LKB1/AMPK Signaling and Peutz-Jeghers Syndrome

Ph.D.
University of Toronto (Canada)

B.Sc.
University of Toronto (Canada)

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Lundquist

Mark Lundquist Ph.D.

Postdoctoral Associate

Research Focus: How extracellular stimuli drive dynamic changes in cytosolic and nuclear structure, and how those changes lead to gene transcription in disease such as breast cancer, pancreatic cancer and melanoma.

Ph.D.
Cornell University

M.S.
The Johns Hopkins University

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Photo of Oksana Mashadova

Oksana Mashadova

Research Technician

Research Focus: Investigating novel PDAC therapies.

Mullarky

Edouard Mullarky

Visiting Graduate Student

Research Focus: Cancer cell metabolism with a focus on the serine synthesis pathway.

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Bryan Ngo

Graduate Student

Research Focus: (1) Defining the molecular basis of LKB1-HIPPO pathway mediated tumor suppression in KRAS-Driven Non-Small Cell Lung Cancer. (2) Identifying molecular convergence points between the Hippo Pathway and Phosphoinositide (PI) Kinases, with an emphasis on the Type II PI Kinase, PIP4K2s.

B.S.
University of California, Irvine

Noch

Evan Noch M.D., Ph.D.

Neurology Resident

Research Focus: The role of oncogenes in the regulation of oxygen and glucose metabolism in the pathogenesis of glioblastoma and medulloblastoma.

Ph.D.
Temple University School of Medicine

M.D.
Temple University School of Medicine

B.S.
New York University

Photo of Shivan Ramsamooj

Shivan Ramsamooj

Research Technician

Research Focus: Analysis of the biochemistry behind folate metabolism in cell growth.

Photo of Hye-seok Shim

Hyeseok Shim

Visiting Graduate Student

Research Focus: Identifying the role of PIP4K2C in vivo and developing type II PIP4K inhibitors

Diana Wang

M.D., Ph.D. student

Research Focus: Pancreatic adenocarcinoma, PIP4K, metabolomics, kras, radiometabolomics

Photo of Jenny Wong

Jenny Wong

Research Technician

Research Focus: Kinase signaling and developing drugs to target the phosphoserine pathway.

Photo of David Wu

David Wu B.S.

Research Focus: Maintaining mouse colonies and mouse experiments

B.S.
Stony Brook

Photo of Zhiwei

Zhiwei Yang B.S.

Research Specialist

Phone: (212) 746-3080
Yang

Jonathan Yang M.D.

Radiation Oncology Fellow

Research Focus: Development of a therapeutic protocol and exploring the radiosensitizing mechanisms of PI5P4K inhibition in breast cancer.

M.D.
Yale University

B.S.
University of North Caroline-Chapel Hill

Yun

Jihye Yun Ph.D.

Postdoctoral Associate

Research Focus: Metabolic pathways and enzyme regulation by oncogenes in colorectal cancer

Ph.D.
The Johns Hopkins University

M.S.
Korea Advanced Institute of Science and Technology (Korea)

B.S.
Sogang University (South Korea)

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Zheng

Yuxiang Zheng Ph.D.

Postdoctoral Associate

Research Focus: The regulation of one-carbon metabolism by growth factor signaling.

Ph.D.
Vanderbilt University

B.S.
Nanjing University (China)

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Contact Us

Meyer Cancer Center
Belfer Research Building
413 E 69th St.
Room 1362, Box 50
New York, NY 10021
Phone: (646) 962-6297