Cantley Lab

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Dr. Cantley and his team in their lab at Weill Cornell Medical College.

Lab Team

The Cantley lab welcomes a diverse set of talents and fosters an interdisciplinary approach in its attempts to translate fundamental scientific discoveries into clinical innovations.

Principal Investigator

Lewis Cantley

Lewis C. Cantley, Ph.D.

Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medical College/Ronald P. Stanton Clinical Cancer Program at NewYork-Presbyterian , Professor of Cancer Biology in Medicine
Lewis Cantley has made significant advances in cancer research, stemming from his discovery of the signaling pathway phosphoinositide 3-kinase (PI3K) in 1984. His pioneering research has resulted in revolutionary treatments for cancer, diabetes and autoimmune diseases. The author of over 400 original papers and more than 50 book chapters and review articles, Dr. Cantley is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. He graduated summa cum laude with a B.S. in chemistry from West Virginia Wesleyan College (1971) and obtained a Ph.D. in biophysical chemistry from Cornell University (1975). He conducted postdoctoral research at Harvard University, where he was appointed assistant professor of biochemistry and molecular biology in 1978. He became a professor of physiology at Tufts University in 1985, but returned to Harvard Medical School as professor of cell biology in 1992. He became chief of Harvard’s new Division of Signal Transduction, and a founding member of its Department of Systems Biology in 2002. In 2007, he was appointed director of the Beth Israel Deaconess Cancer Center. He joined the faculty of Weill Cornell Medical College and NewYork-Presbyterian Hospital in 2012.

Lab Members

Headshot of Jacqueline  Gonzalez

Jacqueline Gonzalez B.Sc.

  • Administrative Assistant to Dr. Lewis Cantley
Phone: (646) 962-6132
Monica Rosen. Cantley lab manager

Monica Rosen

  • Lab Manager
  • B.S.
    Pennsylvania State University
Phone: (646) 962-6136
Headshot of Solomon Amadiume

Solomon Amadiume

  • Research Technician I
  • B.S.
    State University of New York at Plattsburgh
Headshot of Samuel Bakhoum

Samuel Bakhoum M.D., Ph.D.

  • Clinical Fellow
Research Focus: Examining the role of chromosomal instability in cancer evolution. Using in vitro and in vivo models to understand the role of chromosome segregation errors in cancer metastasis and drug resistance.

  • B.S.
    Simon Fraser University, BC, Canada
  • MD., Ph.D.
    Dartmouth Medical School
Headshot of Julie-Ann Cavallo-Fleming

Julie-Ann Cavallo-Fleming Ph.D.

  • Senior Research Technician
Research Focus: The role of chromosomal instability (CIN) in breast and lung cancer metastasis.

  • B.S.
    Fordham University
  • M.S.
    University of Medicine and Dentistry of New Jersey
  • Ph.D.
    Stony Brook University
Headshot of Marcus Goncalves

Marcus Goncalves M.D., Ph.D.

  • Endocrinology Fellow
Research Focus: Skeletal muscle growth and metabolism, Muscle loss in cancer, Glucose metabolism, Insulin signaling, PI5P4K

  • M.D., Ph.D.
    University of Pennsylvania School of Medicine
  • BS, MSE
    Johns Hopkins University
Hodakoski

Cindy Hodakoski Ph.D.

  • Postdoctoral Associate
Research Focus: Studying glucose dependence and AMPK signaling regulation in lung cancer cells.

  • Ph.D.
    Columbia University
  • B.A.
    University of Scranton
Hopkins

Ben Hopkins Ph.D.

  • Postdoctoral Associate
Research Focus: The role of insulin signaling in pancreatic cancer; how insulin signaling impacts KRAS driven disease progression and how these signaling networks can be targeted for therapeutic benefit.

  • Ph.D.
    Columbia University
  • M.A.
    Yale University
  • B.A.
    Amherst College
Headshot of Katie (Seo-Kyoung) Hwang

Katie (Seo-Kyoung) Hwang

  • Research Specialist
Research Focus: Skeletal muscle growth and metabolism, muscle loss in cancer, glucose metabolism, insulin signaling, PI5P4K

Johnson

Jared Johnson Ph.D.

  • Postdoctoral Associate
Research Focus: Molecular and biochemical approaches to the signaling and metabolism of cancers

  • Ph.D.
    Cornell University
Headshot of Qian Li

Qian Li Ph.D.

  • Research Associate
Research Focus: The regulation of one-carbon metabolism by growth factor signaling.

Headshot of Ting-Yu (Molly) Lin

Ting-Yu (Molly) Lin

  • Graduate Student
Research Focus: Regulation of NRF2 in the Non-Small Cell Lung Cancer (NSCLC).

  • M.S.
    National Taiwan University (Taipei, Taiwan)
Valbona Luga

Valbona Luga Ph.D.

  • Postdoctoral Associate
Research Focus: LKB1/AMPK Signaling and Peutz-Jeghers Syndrome

  • Ph.D.
    University of Toronto (Canada)
  • B.Sc.
    University of Toronto (Canada)
Lundquist

Mark Lundquist Ph.D.

  • Postdoctoral Associate
Research Focus: How extracellular stimuli drive dynamic changes in cytosolic and nuclear structure, and how those changes lead to gene transcription in disease such as breast cancer, pancreatic cancer and melanoma.

  • Ph.D.
    Cornell University
  • M.S.
    The Johns Hopkins University
Headshot of Yilun Ma

Yilun Ma

  • Research Technician I
Research Focus: Using molecular and biochemical techniques to investigate cancer signaling and protein dynamics.

  • B.S.
    Cornell University
Mullarky

Edouard Mullarky Ph.D.

  • Postdoctoral Associate
Research Focus: Cancer cell metabolism with a focus on the serine synthesis pathway.

Headshot of Charles Murphy

Charles Murphy

  • Graduate Student
Research Focus: Develop precision medicine pipelines and tools for a mouse model of triple negative breast cancer with the aim to discover new preventative and treatment strategies for human breast cancer patients.

  • B.S.
    University of Wisconsin—Milwaukee
Headshot of Bryan Ngo

Bryan Ngo

  • Graduate Student
Research Focus: (1) Defining the molecular basis of LKB1-HIPPO pathway mediated tumor suppression in KRAS-Driven Non-Small Cell Lung Cancer. (2) Identifying molecular convergence points between the Hippo Pathway and Phosphoinositide (PI) Kinases, with an emphasis on the Type II PI Kinase, PIP4K2s.

  • B.S.
    University of California, Irvine
Noch

Evan Noch M.D., Ph.D.

  • Neurology Resident
Research Focus: The role of oncogenes in the regulation of oxygen and glucose metabolism in the pathogenesis of glioblastoma and medulloblastoma.

  • Ph.D.
    Temple University School of Medicine
  • M.D.
    Temple University School of Medicine
  • B.S.
    New York University
Headshot of Marcia Paddock

Marcia Paddock M.D., Ph.D.

  • Clinical Fellow in Hematology and Oncology
Research Focus: Characterizing phosphatidylinositol phosphate signaling in cell growth and survival with the goal of discovering novel targets for cancer therapeutics. Focus on lipid kinases, PIP4K2 and PLC families of proteins.

  • M.D., Ph.D.
    University of Washington, Seattle, WA
Headshot of Shakti Ramsamooj

Shakti Ramsamooj

  • Research Technician I
Research Focus: Characterizing extracellular vesicles in vitro and in mouse cancer models. Analysis via viral infection, bioluminescence, western blotting, and proteomics.

  • B.S.
    New York University
Headshot of Anita Robin

Anita Robin

  • Research Technician II
Research Focus: Developing drugs to target the phosphoserine pathway.

  • B.S.
    Dickinson College
  • M.S.
    University of Nottingham
Headshot of Ruth Silimon

Ruth Silimon

  • Graduate Student
Research Focus: Skeletal muscle growth, metabolism, and muscle loss in cancer.

Headshot of Janet Sun

Janet Sun

  • Research Technician II
Research Focus: Type-2 PIP kinases and kinase signaling

  • B.S.
    St. Lawrence University
Headshot of Diana Wang

Diana Wang

  • M.D., Ph.D. student
Research Focus: Pancreatic adenocarcinoma, PIP4K, metabolomics, kras, radiometabolomics

  • B.S.
    Massachusetts Institute of Technology
Photo of Jenny Wong

Jenny (Chan Ying) Wong

  • Research Technician II
Research Focus: Kinase signaling

  • M.S.
    City College of New York
  • B.S.
    City College of New York
Headshot of David Wu

David Wu

  • Research Technician II
Research Focus: Maintaining mouse colonies and mouse experiments

  • B.S.
    Stony Brook
Yang

Jonathan Yang M.D., Ph.D.

  • Radiation Oncology Fellow
Research Focus: Development of a therapeutic protocol and exploring the radiosensitizing mechanisms of PI5P4K inhibition in breast cancer.

  • M.D.
    Yale University
  • B.S.
    University of North Caroline-Chapel Hill
Headshot of Isaiah Yim

Isaiah Yim

  • Research Technician I
Research Focus: The role of PIP4K2 on the regulation of metabolism in glioma tumor cells.

  • B.S.
    University of Michigan
Yun

Jihye Yun Ph.D.

  • Instructor
Research Focus: Metabolic pathways and enzyme regulation by oncogenes in colorectal cancer

  • Ph.D.
    Johns Hopkins University
  • M.S.
    Korea Advanced Institute of Science and Technology (Korea)
  • B.S.
    Sogang University (South Korea)
Zheng

Yuxiang Zheng Ph.D.

  • Postdoctoral Associate
Research Focus: The regulation of one-carbon metabolism by growth factor signaling.

  • Ph.D.
    Vanderbilt University
  • B.S.
    Nanjing University (China)

Weill Cornell Medicine
Cantley Lab
Weill Cornell Medical College Meyer Cancer Center
Belfer Research Building
413 E 69th St.
Room 1362, Box 50
New York, NY 10021 Phone: (646) 962-6297